Ben Singer
Ben Singer joined the lab in 2003. He is working on the PhD portion of his MD/PhD as a member of the Neuroscience Graduate Program. This semester he is also a teaching assistant for medical gross anatomy.
Ben divides his time between two projects in the lab, both of which analyze neural activity from both a spatial and temporal perspective. In his project examining information processing in the olfactory system, Ben uses a photodiode array and voltage sensitive dyes to record population activity across the surface of the olfactory bulb. Using this approach, we are examining the role of modulatory input from central odor processing regions in the olfactory bulb.
In collaboration with Miron Derchansky and Peter Carlen at the University of Toronto , Ben is also studying the spatiotemporal dynamics of seizures in an in vitro model system. Using time series analysis tools developed in the lab as well as computational models of neural networks, this work is examining the role that heterogeneity in connectivity and excitability throughout the hippocampus plays in the genesis, propagation, and extinction of seizure activity.
Publications
Benjamin H. Singer, Miron Derchansky, Peter L. Carlen, and Michal Zochowski (2006) Lag synchronization measures dynamical processes underlying progression of seizure states. Physical Review E , 73 021910.
Soyoun Kim, Benjamin H. Singer and Michal Zochowski (2006) Changing roles for temporal representation of odorant during the oscillatory response of the olfactory bulb. Neural Computation , 18(4) 794-816.
Featured Results
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Response of the olfactory bulb to paired-pulse stimuli. I1: response to first pulse. I2: response to second pulse ipsilateral to the first. C2: response to second pulse contralateral to the first. |
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Local field potential recordings of a seizure-like event recorded from four locations along the longitudinal axis of the hippocampus. |
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